|
Transabdominal US Evaluation of Esophageal Varices: as a Prospective Screening Test |
|
Seung Yon Baek, M.D., Sun Wha Lee, M.D. |
|
Department of Radiology, College of Medicine, Ewha Womans University |
|
PURPOSE : To evaluate the efficacy of transabdominal ultrasonography to diagnose esophageal varices and to predict
the grade of varices as a screening test for cirrhotic patients.
MATERIALS and METHODS : Transabdominal ultrasonography was performed in 41 cirrhotic patients to evaluate
esophageal varices prospectively. We measured thickness of the anterior distal esophageal wall three times and
calculated the mean thickness. We evaluated the pattern of the wall (smooth or irregular), the presence of
Doppler signal flow, the pattern and direction and velocity of Doppler signal flow in the esophageal wall. We
considered the mean thickness of the esophageal wall in 44 patients without liver diseases to normal control.
The endoscopic grade(grade 1 to 4) of esophageal varices was considered as a gold standard. We analyzed the
statistical difference between groups of esophageal varices and the normal control group using ANOVA and
multiple comparison method and t-test.
RESULTS : Mean thickness of the normal and variceal group was 2.7±0.7mm and 5.2±1.8mm with statistical difference
(p<0.001). Mean thickness between the normal group and each of the three grades of variceal group was
statistically different (p<0.001) respectively. Mean thickness of grade I (N=19), grade II (N=10) and grade III
and above (N=12) was 4.2±1.2mm, 4.9±1.1mm, 7.0±1.8mm respectively and for higher grades, the
esophageal wall became thicker. There was statistical difference of mean thickness between grade I and grade
III and above, grade II and grade III and above (p<0.001) and no difference between grade I and grade II
(p=0.40). The pattern of the esophageal wall was irregular in 17(41%) patients and the presence of Doppler signal
flow was found in 8(20%) patients. If the diagnostic criteria of mean thickness to diagnose varices was
3.5mm, accuracy, sensitivity, specificity, positive predictive value and negative predictive value was 85.9%,
82.9%, 88.6%, 87.2%, 84.8% respectively.
CONCLUSION : Transabdominal ultrasonography is an efficient prospective screening test to diagnose varices and to |
|
Keyword : Esophagus, US; Esophagus, varices |
|
pdf파일 : K20200029.pdf
|
|